Native Human and Animal Proteins

IMMUNOGLOBULINS

As a group, immunoglobulins play an essential role in the immune system by recognizing antigens and targeting them for destruction or removal.

Immunoglobulins have a potentially wide utility as biomarkers from serum IgG levels indicating general immune response to IgE as a biomarker for asthma to Rheumatoid Factor IgM indicating general inflammation or possibly Rheumatoid Arthritis.

ART offers all five immunoglobulin isotypes: IgA, IgD, IgE, IgG, and IgM as well as the four IgG subclasses: IgG1, IgG2, IgG3, and and IgG4. Immunoglobulin fragments such as IgG-Fc, IgG-Fab, and IgMFc5u are also available.

TRANSFERRIN & APOTRANSFERRIN

Athens Research and Technology (ART) purifies a variety of choices of high-purity, functional Transferrin and ApoTransferrin from human plasma and can provide multi-kilogram quantities. There proteins are offered in numerous formulations – including custom preparations – such as partially to fully saturated, heat-treated, Low Endotoxin Level, as well as bioburden and mycoplasma tested. Holo/ApoTransferrin are important proteins which act as key transport factors and are frequently used in defined cell culture media. ART’s top-of-the-industry products are relied upon as components for large-scale media production by numerous major companies as well as by smaller manufacturers. In addition to our human options, we also offer a range of animal model alternatives derived from species such as monkey, rat and mouse.

APO/LIPOPROTEINS

Athens Research and Technology (ART) purifies high-quality Lipoproteins in-house from fresh, non-frozen human plasma. Our process ensures intact lipid components to provide optimal results for our customers’ production and research. Our Apolipoproteins are remarkably pure, fully delipidated proteins which we derive from our very own plasma Lipoproteins. ART’s products are tests to describe their lipid content and assess their purity, ensuring rigorous product specifications are met. Our Apo/Lipoproteins have a long, proven track record in research and industrial applications. To meet your lab’s goals, ART’s products may be used in cell culture, research for Alzheimer’s and cardiovascular disease, as antigens, and also for standards.

ENZYMES & INHIBITORS

The enzymes and inhibitors manufactured by ART are the gold standard in research reagents. Isolated from natural sources, such as human or animal tissue and blood components, our proteins are native, active and exceptionally pure. ART enzymes and inhibitors meet stringent activity specifications which are ensured by our QC testing. Our team is always ready to assist with any technical questions that may arise from your assays.

Our products have been used to establish world-wide standards for disease diagnosis, so ART is the trusted, first choice to help support your research or manufacturing goals.

CUSTOM PROJECTS

Often research requires reagents not commercially available. For example, you are able to source normal plasma immunologicals, but you need them from plasma positive for West Nile virus. You’ve read a protocol yielding 25 ug of a protein, but your project requires 5 mg, and you don’t have the extra personnel or equipment to do the purification. ART welcomes these types of custom projects. Call us with your research need and we will design and price a research protocol which we believe will offer the highest probability of obtaining the reagent you need.

Regular requests from our customers include: assay development, kinetic studies, isoform sperarations, purifications from cell culture, and so on. We purify proteins or protein complexes. ART’s proteins are also used in proof-of-concept studies by researchers developing biotherapeutics. Just tell us what you need and we’ll prepare a research plan and budget for your project.